Package: depower 2026.11.11

depower: Power Analysis for Differential Expression Studies

Provides a convenient framework to simulate data, run hypothesis tests, estimate power, and plot the results for differential expression studies. The simulation-based framework is described in Klamer and Yu (2026) <doi:10.1177/11769351261431247>. Outcomes may be lognormal, negative binomial, or bivariate negative binomial. Supported designs are one-sample, independent two-sample, and dependent two-sample comparisons. Built-in tests include t-tests, Wald tests, and likelihood ratio tests. User-defined tests are also accepted. The significance level can be set to control the per-family error rate or the family-wise error rate. Negative binomial methods are described in Yu, Fernandez, and Brock (2017) <doi:10.1186/s12859-017-1648-2> and Yu, Fernandez, and Brock (2020) <doi:10.1186/s12859-020-3541-7>.

Authors:Brett Klamer [aut, cre], Lianbo Yu [aut]

depower_2026.11.11.tar.gz
depower_2026.11.11.zip(r-4.7-any)depower_2026.11.11.zip(r-4.6-any)depower_2026.11.11.zip(r-4.5-any)
depower_2026.11.11.tgz(r-4.6-any)depower_2026.11.11.tgz(r-4.5-any)
depower_2026.11.11.tar.gz(r-4.7-any)depower_2026.11.11.tar.gz(r-4.6-any)
depower_2026.11.11.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
depower/json (API)

# Install 'depower' in R:
install.packages('depower', repos = c('https://bklamer.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://bitbucket.org/bklamer/depower

On CRAN:

Conda:

4.34 score 63 scripts 322 downloads 27 exports 75 dependencies

Last updated from:b4057e799f. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develOK253
source / vignettesOK246
linux-releaseOK192
macos-releaseOK192
macos-oldrelOK174
windows-develOK358
windows-releaseOK325
windows-oldrelOK273
wasm-releaseOK134

Exports:add_power_ciadd_power_piasymptoticeval_power_cieval_power_piglm_nbglmm_bnbglmm_poissonlrt_bnblrt_nbmle_bnb_altmle_bnb_nullmle_nb_altmle_nb_nullnll_bnb_altnll_bnb_nullnll_nb_altnll_nb_nullpowersim_bnbsim_log_lognormalsim_nbsimulatedt_test_pairedt_test_welchwald_test_bnbwald_test_nb

Dependencies:backportsBHbootbroomcallrcharportclicolorspacecowplotcpp11crayonDerivdoBydplyrfarverforecastfracdiffgenericsggplot2glmmTMBgluegtableisobandlabelinglatticelifecyclelme4lmtestmagrittrMASSMatrixmgcvminqamodelrmultidplyrmvnfastnlmenloptrnnetnumDerivotelpbkrtestpillarpkgconfigprocessxpspurrrqs2R6rbibutilsRColorBrewerRcppRcppArmadilloRcppEigenRcppParallelRdpackreformulasrlangRTMBS7sandwichscalesstringistringrtibbletidyrtidyselecttimeDateTMBurcautf8vctrsviridisLitewithrzoo